|HRT & Breast Cancer|
HRT Users With Breast Cancer Had Smaller Tumors Than HRT Nonusers
North American Menopause Society19th Annual Scientific Meeting
New data reveal that women diagnosed with breast cancer while using hormone therapy had smaller tumors and an earlier stage of breast cancer, compared with their non-using peers. The researchers also reported a higher five-year survival rate for women with breast cancer using HT.
Jing-Hong Kim, MD, and Mee-Ran Kim, MD, obstetrician/gynecologists at The Catholic University of Korea, conducted a study to determine associations between HT use and prognostic indicators of breast cancer among postmenopausal women who had and had not been treated with HT. Using medical records between 1995 and 2004, the researchers collected data on various characteristics, such as age at diagnosis and menopause, method of treatment, size of tumor and mortality rate.
Women using HT had a higher operative menopause rate of 41.38% compared with 16.84% among non-users (P=.0014). HT users also had a higher well differentiation rate compared with non-users вЂ” 53.85% vs. 13.36% (P=.0026).
More than half (55.17%) of women treated with HT had tumors in stage T1 or lower compared with 28.57% of women who did not take hormones.Women using HT also had smaller tumors than nonusers (P=.0032).
These findings were presented at the North American Menopause Society 19th Annual Scientific Meeting in Orlando by Katie Kalvaitis
Michelle P. Warren, MD