April 15th 2011 - Issue 2045                                                                                                                                 The Newsletter Is Also Available HERE!

More Than A Quarter Of U.S. Children Are On Prescription Drugs
High blood pressure, high cholesterol, diabetes, trouble sleeping, depression, hyperactivity: it's hard being a kid. Over a quarter of our country's children are now on long-term prescription drug regimens, and the percentage will only continue to increase. The Wall Street Journal reports:

Gage Martindale, who is 8 years old, has been taking a blood-pressure drug since he was a toddler. "I want to be healthy, and I don't want things in my heart to go wrong," he says.

And, of course, his mom is always there to check Gage's blood pressure regularly with a home monitor, and to make sure the second-grader doesn't skip a dose of his once-a-day enalapril.

These days, the medicine cabinet is truly a family affair. More than a quarter of U.S. kids and teens are taking a medication on a chronic basis, according to Medco Health Solutions Inc., the biggest U.S. pharmacy-benefit manager with around 65 million members. Nearly 7% are on two or more such drugs, based on the company's database figures for 2009.

Doctors and parents warn that prescribing medications to children can be problematic. There is limited research available about many drugs' effects in kids. And health-care providers and families need to be vigilant to assess the medicines' impact, both intended and not...

The 5 Most Profitable Drugs: They Never Cure You
Writer Keegan Hamilton investigates the controversy surrounding ibogaine, the experimental hallucinogen drug that has helped kick meth and heroin addictions.

Ibogaine is illegal, even though its power to cure addicts has been proven. Hamilton's story describes the many reasons the medical establishment and the government are wary of Ibogaine, despite its benefits, but one of them really stood out:

Because Ibogaine is an outright cure, drug companies want nothing to do with it.

Martin Kuehne, a chemist at the University of Vermont, is quoted in the story, saying, "Pharmaceutical companies don't like cures. Really, they don't -- that's the sad thing. They like treatment. Something for cholesterol or high blood pressure that you take for years and years, every day. That's where the profit is."

When we read that, a light went on. The worst thing for a drug company is a pill you take that completely cures you of your ailment with one dose, right? Where's the money in that?

So, with that in mind, we thought we'd test Kuehne's theory, and look at the five most profitable drugs in the United States...

In Breast Milk, Clues to Risk of Breast Cancer
What drives the spread of Breast Cancer?

A woman's breast milk holds the potential to assess her risk of developing breast cancer, according to preliminary research presented Monday.

In her research, Kathleen Arcaro, an associate professor of environmental toxicology at the University of Massachusetts in Amherst, collected milk samples from both breasts of about 250 nursing women who had a previous breast biopsy or were scheduled to have a lump biopsied. In most cases the lumps were found to be benign, although cancer was found in 13 women.

Using the milk samples, Dr. Arcaro and her team of researchers isolated what are known as epithelial cells and then looked at the DNA inside them. Certain genes in some of the samples showed changes, which are known as methylation, that are thought to precede the development of cancer. A previous study conducted by Dr. Arcaro using breast milk from healthy women showed few changes in the DNA of certain genes.

The research is focusing on changes in 12 genes that other researchers have shown are involved in the development of breast cancer. Dr. Arcaro has analyzed three of the 12 genes so far...

US FDA Rejects CSL's Gardasil For Older Women
US regulators have turned down Merck & Co Inc's bid to extend use of the CSL Ltd-developed cervical cancer vaccine Gardasil to older women.

The pharmaceutical giant had hoped to get approval for the vaccine to be used by women between the ages of 27 and 45.

Merck said that the Food and Drug Administration concluded that Gardasil has not been shown to prevent HPV-related cervical cancers in women over the age of 26 and the drug's label has been updated to reflect that decision.

Gardasil is approved for use in girls and young women 9 through 26 years of age.

Merck has the rights to market Gardasil outside Australia, with royalties paid to CSL on sales made.

CSL received royalty payments of $45 million in the first half...

The Wiley Protocol In Four Continents!
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Shannon

just had my first gyn appointment since being on the Wiley Protocol. The last time I went to her (several years ago), I had an irregular heartbeat (she checks more than just the Pap, etc), and Dr. Chen had also noted the irregular heart beat several times, but it seems it's now gone. She listened three times to be positive, but she says it's no longer there. She also found my thyroid "perfect", my lungs clear, etc, and during my pelvic exam, she said I was pink, moist, and she highly doubted anything will come back negative on the pap or std labs. She said in fact, that I appeared "radiant" and perfectly healthy. Ah, lovely music to my ears. I had taken a couple of newsletters with me and my WP, but she didn't want to see it, said she knew all about it. Said it was fine if I liked it and certainly I seemed to be glowing, but she personally would not recommend it because she felt it was "unnecessarily complicated" - I didn't say anything back, but I'm sure she meant the cycling of the hormones, but it makes sense to me - your body cycles them, why wouldn't you want to match that as closely as one can when replacing them...

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Pat Fulmer

Just wanted to let you know I have been on the Wiley Protocol for 6 years now and never felt better. I participated in the Nurses Health Study ( I am a retired RN) 15 years ago at the age of 36. Both blood and urine studies were done. Now, 15 years later, they have asked me to participate again with blood and urine samples. Questions were asked specifically about hormones and I proudly listed Wiley (estrogen, progesterone and testosterone). Hopefully the results will get Wiley and HRT good news...

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Q:  Why do people wake in the middle of the night and have trouble falling back to sleep?

A:   There are many reasons; a common one is light. When you turn on the bathroom light, dopamine is generated to help you think, and it makes you more awake. Things that help include making sure you are in the dark, there is no clock face showing, and you've restricted fluids before bedtime. In addition once the sex hormones begin to fall off, disruption in one's sleep pattern is the most common complaint.

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