Benefits for me of Wiley protocol:  clear thinking, calm mood, no lower back pain, no "creepy crawly" feelings in both legs, no foot and ankle pain which kept me awake at night, reduced pain in my L arm and neck (from long ago auto accident), no sharp pains to my ovaries and uterus at random, improved digestion, no fatigue, better planning abilities, more able to get out and take long walks, happier. 

Compared to the long list of annoying aches and pains I usually have, life on the Wiley Protocol is great. I did have what appears to be muscle pain in my right leg in the beginning months, which is subsiding now.