The Wiley Protocol

Link: http://www.thewileyprotocol.com/Hormone-Replacement-Therapy/

Bioidentical hormones has basically become a catch all phrase for anything that is not a synthetic hormone. What the word actually means is commonly applied to look-alike molecules derived from “natural” plants that are substituted for our own endogenously-produced hormone molecules. So “natural” or bioidentical hormones are made in a laboratory. How? By converting natural plant compounds from wild yams and soybeans into chemical molecules that are identical to those made in the human body (17-beta estradiol, progesterone, or testosterone hormones.)

In actuality, these sources of plant hormones mimic the chemical structure of hormones produced by a human body, with the premise that the body can’t distinguish these "created" bio-identical hormones from the ones the female ovaries "produce" on their own naturally.

Bio-identical hormones are available in standardized tablets, patches, compounded creams, gels and injectable prescriptions.

Link: http://www.thewileyprotocol.com

In the 70's, when Provera was invented, Premarin, the "Prem" in Prempro, was prescribed alone. This low-dose chronic horse estrogen caused uterin cancer by fostering an overgrowth of the lining of the uterous. Originally, a doctor aiming to replace hormones only prescribed estrogen replacement therapy (ERT). But once the epidemic increase of uterine cancer was identified, instead of pulling Premarin from the shelves, Upjohn, the original maker of MPA, invented another drug out of natural progesterone.

The molecule of natural progesterone found in a compound called genistein in plants was chemically altered into a patentable drug that has been proven to have life-threatening side effects like heart disease, breast cancer, stroke, and dementia. The two drugs were eventually packaged together and remarketed as PremPro to prevent the horse estrogen from causing uterine cancer, and increase the market share to women with uteruses.

However, unlike real progesterone, which has a rhythmic, cyclical presence in your body two weeks out of every month, if you take Prempro, you recieve Provera every day. In actuality this combination of horse estrogen and fake progesterone can't ever recreate a normal cycle, so although it's marketed as HRT, it's not. It's not really hormone replacement for two reasons: 1) because it's a drug, and 2) because it's prescribed in a static dose, which has no resemblance to what used to go on hormonally in your body when you were in your prime.

In the end, the static, chronic dose of a progestin like Provera in a combination dose with an animal-source estrogen like Premarin blocks the horse estrogen's effect every day. So any benefits known to result in heart, brain, and breast from estrogen are lost or diminished. Even though this combination drug can cause breast cancer, heart disease, and dimentia, it's still widely available to women all over the world.

(Source: Sex, Lies, and Menopause: The Shocking Truth about Synthetic Hormones and the Benefits of Natural Alternatives, by T.S. Wiley

Link: http://www.thewileyprotocol.com

The chief medical officer for the American Cancer Society now says that the benefits of early detection are often overstated. The article, "Benefits and Risks of Cancer Screening Are Not Always Clear, Experts Say"
by Tara Parker-Pope for the New York Times, October 22, 2009 said, "You would have to screen 1000 women ages 50 and older for 10 years in order to avert one additional death from breast cancer, compared to a similar number who are not screened." Other highlights included ...

"In the case of prostate cancer, for every 100 men with diagnoses, as many as 70 have cancers that if left untreated would never have harmed them."

"...the chief medical officer for the American Cancer Society now says that the benefits of early detection are often overstated."

The cancer society says it will continue to revise its public messages about cancer screening as new information becomes available.

Author T.S. Wiley (Lights Out and Sex, Lies, and Menopause) has been saying this for years based on her extensive research, and many of the doctors attending her Two Days Back on Earth environmental endocrinology seminars agree. Quoting from her book, in Chapter 5, p. 97," she stated, "As researchers and journalists, we looked back 150 years at the numbers. The statistics Rose Kushner unearthed also proved that early detection is worthless because breast cancer, statistically, kills half of all women diagnosed with it within five to ten years after diagnosis, no matter how early it’s detected. The statistics have never changed. If women never experienced the hormonal fall-off known as menopause, these cancers might never develop.”

Link: http://www.thewileyprotocol.com

Pharmacists will meet Author T.S. Wiley, who has pioneered the standardization of the patent pending Wiley Protocol® rhythmic, compounded bioidentical hormones at Booth 636 at the 111th Annual Convention and Trade Exposition at the Ernest N. Morial Convention Center, New Orleans, Louisiana from October 17–21, 2009. The company will also announce two new Wiley Protocol® rhythms, Snooz™ - Seasonal Neuroendocrine Optimal Organizational Zeitgeber; Melatonin, and Sparc™ Therapy - Seasonal Pulsatile Adrenal Recalibration; Cortisol capsules.

T.S. Wiley is the developer of the Wiley Protocol rhythmic, compounded bioidentical hormones, and has pioneered the standardization of the patent pending Wiley Protocol and includes standardization of formulation, compounding procedure and color-coded packaging available to physicians and patients at recommended retail prices. The company’s biomimetic hormone protocols must be formulated by a trained and registered compounding pharmacist.

A once-a-year opportunity, the NCPA convention provides exhibits, networking, and entertainment along with more than 20 hours of original and topical continuing education, enabling the nation’s independent
community pharmacists to sharpen their patient care skills and improve business performance throughout the following year.

T.S. Wiley's mission is that any woman, in any city or town, could pick-up her prescription for the Wiley Protocol and it would be exactly the same as every other woman’s, everywhere.

Link: http://www.thewileyprotocol.com

On Sept. 20, 2009 this Los Angeles Times newspaper article by Thomas H. Maugh II prompted women to write regarding their Wiley Protocol bioidentical hormones, which are biomimetically dosed.

"This LA Times article and other media continue to report on the negative outcomes of the Women's Health Initiative (WHI) that validates the elimination the drugs with hormone-like effects," said Dr. Taguchi, an oncologist at Santa Barbara's Sansom Clinic. It was Taguchi who worked with T.S. Wiley on her book Sex, Lies and Menopause, The Shocking Truth About Hormone Replacement Therapy.

She continued, "The WHI study used Premarin and daily PREMPRO (Premarin and the progeSTIN Provera) and not bio-identical estradiol or the real hormone, progeSTERONE. Physicians will continue to lump progesterone together with progeSTINS when discussing "Hormone Replacement Thereapy" until there is definitive research on progesterone. I have been following patients on BHRT in my oncology practice for seven years and not one has developed lung cancer."

The initial Women’s Health Initiative (WHI) ten years ago was a study of more than 161,000 women which was designed to identify the benefits and risks of using hormone restoration therapy to prevent chronic diseases such as heart disease, breast cancer and osteoporosis in postmenopausal women.

Many people, including doctors, still do not realize that the results of WHI Study dealt with only women over 65 who were taking only synthetic hormone replacement therapy which consisted of the drugs PremPro and Premarin only. The study was ended mid-stream in 2002 when WHI investigators found that the risks of this approach using synthetic therapy exceeded the safety limits established at the beginning of the study. They never looked at compounded bio-identical hormones in static doses because they are prescribed and dosed too many different ways. This is yet another reason why T.S. Wiley has standardized the Wiley Protocol.

To read about the different types of hormones, please refer to this section of the Wiley Prototol website referring to bioidentical hormones.

Additionally, here's a video interviewing T.S. Wiley about why hormones are dose dependant.