The Wiley Protocol

Link: http://www.thewileyprotocol.com

Wiley Systems is introducing two new Wiley Protocol rhythms at the American College for Advancement in Medicine (ACAM) this week from November 4-8, 2009 at the Rio Las Vegas hotel, Las Vegas, Nevada.

The rhythmic protocols include Snooz™ - Seasonal Neuroendocrine Optimal Organizational Zeitgeber; Melatonin, and Sparc™ Therapy - Seasonal Pulsatile Adrenal Recalibration; Cortisol capsules. These protocols will be available doctors and pharmacists by December 1, 2009.

Melatonin is a naturally occurring hormone that regulates the circadian rhythms of several biological functions. Cortisol is produced by the pituitary gland makes adrenocorticotropic hormone, or ACTH, which stimulates the adrenal gland, which produces Cortisol. If a person doesn’t have enough ACTH to stimulate the adrenal gland to make Cortisol, or if the adrenal gland is not able to make Cortisol, this person will need to take Cortisol replacement therapy.

“The rhythm of nature is so internalized that every molecular action of every hormone to its receptor, on every gene in every cell, functioning in every organ of your body, hears the cosmic tune,” said T.S. Wiley, author and developer of the Wiley Protcol. “Cortisol, insulin, melatonin, prolactin, progesterone, estrogen, testosterone, and growth hormone all play like the keys of a grand piano in response to environmental sheet music.”

Link: http://www.thewileyprotocol.com

There are a few behavioural ecologists working in Bolivia who have found that wild spider monkeys control their diets in a similar way to humans. These monkeys tightly regulate their daily protein intake, so that it stays at the same level regardless of seasonal variation in the availability of different foods, rather than simply trying to maximize their daily energy intake.

Up until now it was thought humans' eating patterns originated in the Palaeolithic era (between 2.4 million and 10,000 years ago). Tight regulation of daily protein intake is known to play a role in the development of obesity in humans, so this research suggests that the evolutionary origins of these eating patterns in humans may be far older than suspected.

Dr. Annika Felton followed 15 individual monkeys (7 adult males, 8 adult females), conducting continuous observations of the same animal from dawn to dusk, and following each of the monkeys for at least one whole day a month. She recorded everything they did and ate, for how long and she counted every fruit and leaf they ate when possible, then collected samples of what they had eaten from the actual trees the monkeys had chosen. The samples were then dried and sent to the laboratory in Australia where they were analyzed for their nutritional content.

"We found that the pattern of nutrient intake by wild spider monkeys, which are primarily fruit eaters, was almost identical to humans, which are omnivores, . What spider monkeys and humans have in common is that they tightly regulate their daily protein intake,” said Felton. “They appear to aim for a target amount of protein each day, regardless of whether they only ate ripe fruit or mixed in other vegetable matter as well.”

Tight protein regulation is the same for monkeys and humans: if the diet is poor in protein but rich in carbohydrates and fats (energy dense food) individuals will end up ingesting a great deal of energy in order to obtain their protein target, which can lead to weight gain. This 'protein leverage effect' is thought to play a significant role in the human obesity problem found in our modern western society. The monkeys maintained a stable intake of protein, by consuming large amounts of carbohydrates and fats when protein content in the food was low, for instance when their diet consisted entirely of ripe fruit, and consumed far fewer carbohydrates and fats when feeding on items rich in protein.

The results suggest that an adjustment of the nutritional balance of diets as a means to manage human obesity might similarly be an option for mitigating obesity in captive primates.

Link: http://www.thewileyprotocol.com

According to new research from the Medical College of Georgia, estrogen can reduce stroke damage by inactivating protein -- more sepcifically estrogen can halt stroke damage by inactivating a tumor-suppressing protein known to prevent many cancers.

Limor Raz, a fourth-year Ph.D. student in the MCG School of Graduate Studies explains that P53, the protein in the mitochondria, or powerhouse, of the cell, is known as "the guardian of the genome" because it regulates the cell cycle, preventing genome mutation. And the good news is that it appears to prevent cancer by suppressing tumor growth.

Stressful conditions such as a stroke activate p53, which triggers unfavorable changes in the cell including the activation of another protein called PUMA, which signals a cascading effect that destroys the mitochondria and causes cell death, or apoptosis. Estrogen can chemically alter p53 and attenuate the cascade, which leads to reduced stroke damage.

Raz has been working with Dr. Darrell Brann, chief of developmental neurobiology and associate director of the MCG Institute of Molecular Medicine and Genetics. She presented her findings this week at the American Physiological Society conference, which focused on the cardiovascular effects of sex steroids and gender.

She says the next step is to determine why. "We know that it does, and now we need to find out how."

Link: http://www.thewileyptorocol.com

Dr. Patricia Ryan talks about bioidenticals - after she has been involved in researching and learning about hormone therapy since 1993. She was always seeking what was safe, and the science behind what works, but it wasn't until she spoke to T.S. Wiley that she got the answers she had been looking for. Many of her patients were taking bioidenticals, but they were only doing OK, and there were problems.

Ryan switched her patients to the rhythmic dosing of the Wiley Protocol, and began to see improvements after three months with improvements in migrains, libido, vaginal dryness, insomnia and even cholesteral levels. She said, "Plus, nobody has gained weight, which is a big deal to women."

Lab tests are also proving reversals of bone density loss. "It has been a pleasant surprise to see their bones coming back to normal while taking this bioidentical hormone therapy."

Link: http://www.thewileyprotocol.com

Patricia Diorio had developed a pain in her heart area. At 58, and with heart disease in her family, she was worried. As a person involved in complementary medicine and as the producer and host of The Paradigm Shift television and radio shows, Patricia heard about T.S. Wiley and invited her onto her show to talk about her book, Sex, Lies, and Menopause. In the book, Wiley talks about how taking progesterone in a cycle with estrogen could prevent heart disease.

Diorio went on the Wiley Protocol and within a month the pain in her heart region disappeared completely. Patricia Diorio shares her experience on the WP bioidentical hormones.

And in fact, there’s new research from a Danish study featured in Europe’s leading cardiovascular journal proving that overall there was no increased risk of heart attacks in current users of HRT compared to women who had never taken hormone replacement. This study also states a combined cyclic regiment with monthly bleeding creates a lower cardiovascular risk for women than continuous-combined estrogen/progesterone therapy, which does not cause a menstrual bleed.

Wiley believes this research is significant validation of the value of cyclical (estrogen, followed by a combination of estrogen and progesterone) hormone replacement therapy and that biomimetic hormone restoration therapy (BHRT) could actually be safer than statically dosed continuous-combined alternatives.