About TS Wiley

Wiley Protocol Rhythmns

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T.S. Wiley is the author of “Sex, Lies & Menopause,” Harper Collins, 2003, the hypothesis of which explains why postponing marriage and motherhood, women have accelerated the aging process and put themselves

in the bull's eye for breast cancer. The book also examines the introduction of the birth control pill in the early 1960’s and the impact of not breast-feeding our young. In her previous book, “Lights Out: Sleep, Sugar and Survival, ” Pocket Books, Simon and Schuster, 2000, Wiley succinctly and logically argues that electricity and the light bulb put us out of sync with nature as the ultimate "endocrine disruptors".

People spent summers, before electric lights, sleeping less and eating heavily in preparation for winter because the light triggered the hunger for carbohydrates. Now, light is available 24 hours a day. Heating and air-conditioning climate control our hormonal responses to consume carbohydrates now available year round. This is the scenario for obesity, Type II diabetes, and depression.

In Wiley’s opinion, sleep is the best medicine. T.S. Wiley has also published peer-reviewed scientific papers in molecular oncology and endocrinology, as well as lecturing globally and teaching physicians Environmental Endocrinology in Planetarium settings around the world. Her newest work in process is "Manthropology", exploring how medicine and modern life are killing men. Find out more about the study of bio-identical, bio-mimetic HRT on her website, www.thewileyprotocol.com


Professional Affiliations A member of the New York Academy of Sciences, and the American Anthropological Association, Wiley often lectures, and has been a keynote speaker at the following venues:

* International Hormone Society, "Multi-Phasic, Cyclical Hormone Replacement Therapy with Bio-Identical E2/P4" in December 2005

* Keynote speaker, American College for Advancement in Medicine (ACAM), “Multi-Phasic, Cyclical Hormone Therapy with Bio-Identical E2/P4, Clinical Aspects” in May 2005

* Presenter, World Conference on Breast Cancer, “Natural progesterone and the evolution of breast cancer” in Kingston, Ontario, Canada, 1997.

Wiley has made numerous national radio and television appearances and since 2000 continues to present and lecture on Multi-Phasic, Rhythmic Cyclic BHRT and Hibernation and Metabolic States. Wiley’s Seminar’s on the Natural History of Endocrinology are attended by physicians from all over the world and they are awarded CME credits for her work.


Peer Reviewed Journals

* Stern R, Shuster S, Wiley TS, Formby B. Hyaluronidase can modulate expression of CD44. Exp Cell Res. 2001 May 15; 266(1):167-76. * Formby B, Wiley TS. Bcl-2, survivin and variant CD44 v7-v10 are downregulated and p53 is upregulated in breast cancer cells by progesterone: inhibition of cell growth and induction of apoptosis. Mol Cell Biochem. 1999 Dec; 202(1-2):53-61.

* Formby B, Wiley TS. Progesterone inhibits growth and induces apoptosis in breast cancer cells: inverse effects on Bcl-2 and p53. Ann Clin Lab Sci. 1998 Nov-Dec; 28(6):360-9.

* Formby B, Wiley TS. Insulin modulates expression of the estrogen-induced genes Bcl-2, c-fos and LucCa-2 in MCF-7 breast tumor cells: evidence for association between breast cancer risk and Type 2 diabetes? Diabetes, poster presentation, American Diabetes Association, June 16, 1997.


Projects

* “Protocol for the study of natural progesterone and its clinical effects on advanced metastic cancer.” with Dr. Bent Formby and Dr. Julie Taguchi 1999 (not reported)

* “Randomized, placebo controlled, double blind trial of testosterone in men with elevated age specific PSA and benign prostatic hypertrophy.” with Dr. David Laub and Dr. Julie Taguchi 1999 (as yet unpublished)

* “Natural progesterone for the treatment of multiple forms of cancer.” 1998 (U.S. patent-pending)

* "Insulin for Cosmetic Use" 1999 (U.S. patent)

* "Multi-Phasic, Rhythmic, Cyclic Dosing, The Wiley Protocol" 2004 (U.S. patent pending)

* B.H.O.T. Bio-identical Hormones On Trial: A Comparison of Routes of Administration and Dosing Patterns of Compounded Bio-Identical Hormone Therapy. Study Team: Julie Taguchi, MD, oncologist and clinical researcher, Sansum Clinic, Santa Barbara, California, Janith Williams, DNP, WHNP, RNP, researcher, consultant, clinician and faculty member, Assistant Professor, College of Nursing and Health Sciences, The University of Texas at Tyler. Other teams members include GYN/OB MD's, Functional Medicine MD's, Doctorate of Pharmacy compounding pharmacists, biostatisticians, and 10-12 primary care providers with expertise in care of peri-menopausal and menopausal women. The study has an Advisory Board with nationally recognized content experts and researchers. Study is IRB #Sp2007-27, The University of Texas at Tyler, Tyler , Texas . Study initiated fall 2008.

* "Oral versus Transdermal (cream) Estradiol plus Estriol With Sequential Oral or Transdermal Progesterone, Transdermal Estradiol Patch with Oral Progesterone Versus A Control Arm in Peri-Menopausal Women "(IRB approved pending start date) Projected October 2008